Hormonal changes are involved in some gynecological diseases. Proper functioning of the hypothalamus-pituitary-ovarian (HPO) axis is critical for ovulatory function, as well as growth and differentiation of uterine tissue (myometrium and endometrium)
Menorrhagia is menstrual bleeding that lasts more than 7 days. It can also bleed very heavily. How do you know if you have heavy bleeding? If you need to change your tampon or pad after less than 2 hours or you pass a quarter-sized or larger clot, that’s heavy bleeding.